WEDNESDAY, March 25, 2026 (HealthDay News) — The offspring of mothers who lost pregnancy have an increased risk of cardiovascular disease (CVD) and CVD mortality, according to a study published online March 25. Journal of the American Heart Association.
Where V. Ananth, Ph.D., MPH, of the Rutgers Robert Wood Johnson School of Medicine in New Brunswick, New Jersey, and colleagues conducted a retrospective cohort study using a cohort of risk of placental abruption and cardiovascular events to assess the risks associated with obesity in fatal and nonfatal disease. events To reduce familial confounding, these associations were replicated in sibling analyses.
The prevalence of miscarriage in a cohort of 2,949,992 one-year pregnancies was 1 percent. The offspring were followed for an average of 14.5 years. The researchers found that the infant mortality rate of CVD among births with and without separation was 4 and 1 per 100,000, respectively (adjusted hazard ratio, 4.64). For inoperable CVD, the corresponding rates were 627 and 190 per 100,000 person-years, respectively (adjusted hazard ratio, 2.86). In analyzes restricted to offspring younger than 1 year with CVD events, the risks were higher. In analyzes of sibling pairs, these associations were similar.
“Our study shows that placental abruption should be considered a serious complication for the mother, as well as potentially impacting the child’s cardiovascular health in the future,” Anant said in a statement. “Our study suggests that their children should also be monitored to identify potential complications due to an increased risk of cardiovascular disease.”
